Title : Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.

Pub. Date : 2007 Oct 15

PMID : 17681794






3 Functional Relationships(s)
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1 Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer"s disease therapeutics. piperidine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 With the goal of developing Alzheimer"s disease therapeutics, we have designed and synthesized new piperidine derivatives having dual action of acetylcholinesterase (AChE) and beta-amyloid peptide (Abeta) aggregation inhibition. piperidine acetylcholinesterase (Cartwright blood group) Homo sapiens
3 With the goal of developing Alzheimer"s disease therapeutics, we have designed and synthesized new piperidine derivatives having dual action of acetylcholinesterase (AChE) and beta-amyloid peptide (Abeta) aggregation inhibition. piperidine acetylcholinesterase (Cartwright blood group) Homo sapiens