Pub. Date : 2007 Jul 27
PMID : 17679938
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In Rac1-GTP pull-down assays, treatment of TM cells with 100 nM of JWH015 decreased the activity of Rac1 GTPase activity in a time-dependent manner. | JHW 015 | Rac family small GTPase 1 | Homo sapiens |
| 2 | In Rac1-GTP pull-down assays, treatment of TM cells with 100 nM of JWH015 decreased the activity of Rac1 GTPase activity in a time-dependent manner. | JHW 015 | Rac family small GTPase 1 | Homo sapiens |
| 3 | Pretreatment with 1 microM SR144528, but not with SR141716A, blocked the effect of JWH015 on Rac1 activity. | JHW 015 | Rac family small GTPase 1 | Homo sapiens |
| 4 | This study also shows that JWH015 modulates the activities of Rac1-GTPase and cofilin, which are important signaling molecules for the cytoskeletal and migratory properties of TM cells. | JHW 015 | Rac family small GTPase 1 | Homo sapiens |