Pub. Date : 2007 Aug
PMID : 17666793
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Irinotecan-induced apoptosis is inhibited by increased P-glycoprotein expression and decreased p53 in human hepatocellular carcinoma cells. | Irinotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | SN-38 decreased p53 expression and increased P-gp expression after 120 h, resulting in inhibition of apoptosis. | Irinotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | SN-38-induced P-gp expression was additionally enhanced by p53 decoy oligodeoxynucleotide. | Irinotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |