Pub. Date : 2007
PMID : 17662641
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We show that bleomycin-treated A549 cells exhibit: senescence-like cell morphology; a senescence-associated increase in SA-beta-galactosidase activity; cell cycle arrest; and upregulation of p53 and p21. | Bleomycin | H3 histone pseudogene 16 | Homo sapiens |
| 2 | Our results support the hypothesis that downregulation of caveolin-1 expression affects bleomycin-induced cell cycle arrest and subsequent cellular senescence that is driven by p53 and p21. | Bleomycin | H3 histone pseudogene 16 | Homo sapiens |