Title : High-mannose-specific deglycosylation of HIV-1 gp120 induced by resistance to cyanovirin-N and the impact on antibody neutralization.

Pub. Date : 2007 Nov 10

PMID : 17658575






2 Functional Relationships(s)
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1 High-mannose-specific deglycosylation of HIV-1 gp120 induced by resistance to cyanovirin-N and the impact on antibody neutralization. Mannose Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1
2 For the first time, our data have collectively defined the high-mannose residues on gp120 affecting CV-N activity, and demonstrated that CBA-escape HIV-1 has increased sensitivity to immunoglobulins and sera from HIV patients, and particularly to V3 loop-directed MAbs. Mannose Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1