Title : HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.

Pub. Date : 2007

PMID : 17657162






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 METHODS AND RESULTS: Real-time PCR showed that nicotine induced a dose-dependent increase in mRNA levels for vascular cellular adhesion molecule-1 (VCAM-1)/intercellular adhesion molecule-1 (ICAM-1). Nicotine vascular cell adhesion molecule 1 Homo sapiens
2 METHODS AND RESULTS: Real-time PCR showed that nicotine induced a dose-dependent increase in mRNA levels for vascular cellular adhesion molecule-1 (VCAM-1)/intercellular adhesion molecule-1 (ICAM-1). Nicotine vascular cell adhesion molecule 1 Homo sapiens
3 Fluorescent-activated cell sorting analysis showed that nicotine induced expression of functionally active VCAM-1/ICAM-1, since they increased leukocyte adherence to HCAECs. Nicotine vascular cell adhesion molecule 1 Homo sapiens