Pub. Date : 2007 Oct
PMID : 17656468
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The observed stimulation of DNA adduct formation by ellipticine was attributed to induction of CYP1A1 and/or 1A2-mediated increase in ellipticine oxidative activation to 13-hydroxy- and 12-hydroxyellipticine, the metabolites generating two major DNA adducts in human and rat livers. | ellipticine | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
2 | The observed stimulation of DNA adduct formation by ellipticine was attributed to induction of CYP1A1 and/or 1A2-mediated increase in ellipticine oxidative activation to 13-hydroxy- and 12-hydroxyellipticine, the metabolites generating two major DNA adducts in human and rat livers. | ellipticine | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |