Title : Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle.

Pub. Date : 2007 Oct

PMID : 17656444






1 Functional Relationships(s)
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1 In conclusion, PKC, ERK1/2, and p38 MAPK pathways facilitate microcystin-induced contraction at low Ca2+ concentrations by contributing to the inhibition of MLCP activity either through phosphorylation of MYPT1 or CPI-17 [probably mediated by integrin-linked kinase (ILK)]. microcystin protein phosphatase 1, regulatory subunit 12A Rattus norvegicus