Pub. Date : 2008 Feb
PMID : 17654516
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated whether the tumor promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) may induce melanocyte resistance to TGF-beta. | Tetradecanoylphorbol Acetate | transforming growth factor beta 1 | Homo sapiens |
| 2 | We investigated whether the tumor promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) may induce melanocyte resistance to TGF-beta. | Tetradecanoylphorbol Acetate | transforming growth factor beta 1 | Homo sapiens |
| 3 | Confocal microscopy demonstrated that TGF-beta-induced nuclear accumulation of PKC-alpha was abolished in the presence of TPA at the same time points. | Tetradecanoylphorbol Acetate | transforming growth factor beta 1 | Homo sapiens |
| 4 | Smad-dependent transcriptional activity was suppressed in TGF-beta-treated melanocytes in the presence of TPA, as well as in ALK5 (constitutively active type I TGF-beta receptor)- or Smad3 + Smad4-transfected melanocytes in the presence of Ro-31-8220. | Tetradecanoylphorbol Acetate | transforming growth factor beta 1 | Homo sapiens |