Title : Effect of cytochrome P450 (CYP) inducers on caffeine metabolism in the rat.

Pub. Date : 2007 May-Jun

PMID : 17652830






1 Functional Relationships(s)
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1 Phenobarbital (an inducer of CYP2B and other CYPs and a CYP2C11 inhibitor) moderately stimulated the metabolism of caffeine, but practically did not affect 7-N-demethylation. Phenobarbital cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus