Title : Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro.

Pub. Date : 2007 Oct

PMID : 17652262






1 Functional Relationships(s)
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1 For P-glycoprotein, another member of the ABC transporter family, it is well established that it is at least partly located in cholesterol and sphingolipid-enriched domains of the plasma membrane called "lipid rafts" and that the composition of the membrane lipids may modulate its efflux activity. Cholesterol ATP binding cassette subfamily B member 1 Homo sapiens