Title : Nuclear factor of activated T cell (NFAT) transcription proteins regulate genes involved in adipocyte metabolism and lipolysis.

Pub. Date : 2007 Sep 21

PMID : 17651692






2 Functional Relationships(s)
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1 CsA treatment dramatically reduced the mRNA levels of adipocyte-specific genes (aP2, HSL, PPARgamma, ACS and Adn), compared with control or TNFalpha-treatment, whereas Li(+) pretreatment blocked the inhibitory effects of CsA, and mRNA levels of aP2, HSL, PPARgamma, and ACS were found at or above control levels. Cyclosporine 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens
2 CsA treatment dramatically reduced the mRNA levels of adipocyte-specific genes (aP2, HSL, PPARgamma, ACS and Adn), compared with control or TNFalpha-treatment, whereas Li(+) pretreatment blocked the inhibitory effects of CsA, and mRNA levels of aP2, HSL, PPARgamma, and ACS were found at or above control levels. Cyclosporine 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens