Title : Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells.

Pub. Date : 2007 Sep 1

PMID : 17647244






1 Functional Relationships(s)
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1 RESULTS: Treatment of glioblastoma cells with garlic compounds triggered production of ROS that induced apoptosis with the phosphorylation of p38 MAPK and activation of the redox-sensitive JNK1 pathway. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens