Title : Epinephrine enhances lysosomal enzyme delivery across the blood brain barrier by up-regulation of the mannose 6-phosphate receptor.

Pub. Date : 2007 Jul 31

PMID : 17646643






1 Functional Relationships(s)
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1 Brain uptake of (131)I-P-GUS was significantly inhibited by M6P in a dose-dependent manner, whereas epinephrine failed to increase brain uptake of nonphosphorylated GUS. mannose-6-phosphate glucuronidase, beta Mus musculus