Pub. Date : 2007 Sep
PMID : 17643350
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that the Ca2+-dependent type IV cytosolic phospholipase A2 (cPLA2) was pivotally involved in the COX-2-mediated generation of PGE2 in response to a calcium ionophore, as determined by the use of selected PLA2 inhibitors. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 2 | We found that the Ca2+-dependent type IV cytosolic phospholipase A2 (cPLA2) was pivotally involved in the COX-2-mediated generation of PGE2 in response to a calcium ionophore, as determined by the use of selected PLA2 inhibitors. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 3 | PGE2 biosynthesis elicited by bacterial-derived peptides or by phagocytic stimuli acting on cell surface receptors also showed to be dependent on cPLA2 activity. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |