Pub. Date : 2007 Aug
PMID : 17635184
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The expression of the solute carriers NTCP and OCT-1 is regulated by cholesterol in HepG2 cells. | Cholesterol | solute carrier family 22 member 1 | Homo sapiens |
| 2 | In this study, we analysed the expression of CYP3A4 and three uptake transporters NTCP (SLC10A1), OATP-A/OATP1A2 (SLCO1A2) and OCT-1 (SLC22A1) in HepG2 cells following treatment with cholesterol. | Cholesterol | solute carrier family 22 member 1 | Homo sapiens |
| 3 | While CYP3A4 and OATP1A2 expression was unaffected, cholesterol treatment led to increased levels of NTCP and OCT-1 mRNAs. | Cholesterol | solute carrier family 22 member 1 | Homo sapiens |