Title : Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma.

Pub. Date : 2007 Oct

PMID : 17628016






1 Functional Relationships(s)
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1 Hedgehog pathway blockade by cyclopamine caused a 40%-60% reduction in growth of adherent glioma lines highly expressing Gli1 but not in those lacking evidence of pathway activity. cyclopamine GLI-Kruppel family member GLI1 Mus musculus