Title : Conversion of immunosuppressive monotherapy from cyclosporin a to tacrolimus reverses bone loss in rats.

Pub. Date : 2007 Aug

PMID : 17612778






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1 This study shows that conversion from CsA to tacrolimus therapy leads to a reversal of the CsA-induced bone loss, which can probably be mediated by downregulation of IL-1beta, IL-6, and TNF-alpha production. Tacrolimus tumor necrosis factor Rattus norvegicus