Title : Peripheral site acetylcholinesterase blockade induces RACK1-associated neuronal remodeling.

Pub. Date : 2007

PMID : 17596712






3 Functional Relationships(s)
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1 BACKGROUND: Peripheral anionic site (PAS) blockade of acetylcholinesterase (AChE) notably affects neuronal activity and cyto-architecture, however, the mechanism(s) involved are incompletely understood. Aminosalicylic Acid acetylcholinesterase Rattus norvegicus
2 BACKGROUND: Peripheral anionic site (PAS) blockade of acetylcholinesterase (AChE) notably affects neuronal activity and cyto-architecture, however, the mechanism(s) involved are incompletely understood. Aminosalicylic Acid acetylcholinesterase Rattus norvegicus
3 OBJECTIVE: We wished to specify the PAS extracellular effects on specific AChE mRNA splice variants, delineate the consequent cellular remodeling events, and explore the inhibitory effects on interchanging RACK1 interactions. Aminosalicylic Acid acetylcholinesterase Rattus norvegicus