Pub. Date : 2007 Jun
PMID : 17595889
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C/EBP-dependent fashion. | Rosuvastatin Calcium | interleukin 6 | Homo sapiens |
| 2 | METHODS: Interleukin 6 (IL-6) stimulated human hepatoma cells (Hep3B) and primary human hepatocytes (PHH) were incubated with various concentrations of rosuvastatin (0.3 - 1 microM) for 24 hours. | Rosuvastatin Calcium | interleukin 6 | Homo sapiens |
| 3 | CONCLUSIONS: Our results show a direct inhibitory effect of rosuvastatin on IL-6-induced expression of CRP in liver cells. | Rosuvastatin Calcium | interleukin 6 | Homo sapiens |