Pub. Date : 2007 Jun
PMID : 17591831
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | With regard to the predictive role of Aurora-A, it has been shown that its overexpression disrupts the spindle checkpoint activated by paclitaxel (Taxol) or nocodazole treatment, thus inducing the cells to become resistant to these drugs. | Nocodazole | aurora kinase A | Homo sapiens |
| 2 | The development therefore of small molecules with an Aurora-A inhibition function may make it possible to reduce or block the oncogenic activity of Aurora-A and in addition may improve the survival of oncological patients showing resistance to paclitaxel or nocodazole treatment. | Nocodazole | aurora kinase A | Homo sapiens |
| 3 | The development therefore of small molecules with an Aurora-A inhibition function may make it possible to reduce or block the oncogenic activity of Aurora-A and in addition may improve the survival of oncological patients showing resistance to paclitaxel or nocodazole treatment. | Nocodazole | aurora kinase A | Homo sapiens |