Title : A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove.

Pub. Date : 2007 Sep 15

PMID : 17579185






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 HIF in turn is regulated through its alpha subunit, which under normoxic conditions is hydroxylated on specific prolines and targeted for degradation by the von Hippel Lindau (VHL) protein. Proline von Hippel-Lindau tumor suppressor Homo sapiens
2 HIF in turn is regulated through its alpha subunit, which under normoxic conditions is hydroxylated on specific prolines and targeted for degradation by the von Hippel Lindau (VHL) protein. Proline von Hippel-Lindau tumor suppressor Homo sapiens