Title : Lactate adversely affects the in vitro formation of endothelial cell tubular structures through the action of TGF-beta1.

Pub. Date : 2007 Jul 15

PMID : 17574548






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lactate adversely affects the in vitro formation of endothelial cell tubular structures through the action of TGF-beta1. Lactic Acid transforming growth factor beta 1 Homo sapiens
2 Treatment with 10 mM lactate was accompanied by enhanced mRNA expression and release of TGF-beta1, which also shows anti-angiogenic activity in the model. Lactic Acid transforming growth factor beta 1 Homo sapiens
3 The lactate response on the EC network was diminished by TGF-beta1 neutralization, indicating a causal relationship between lactate and TGF-beta1 in the finely tuned processes of vessel formation and maturation which may also occur in vivo within tumor tissue. Lactic Acid transforming growth factor beta 1 Homo sapiens
4 The lactate response on the EC network was diminished by TGF-beta1 neutralization, indicating a causal relationship between lactate and TGF-beta1 in the finely tuned processes of vessel formation and maturation which may also occur in vivo within tumor tissue. Lactic Acid transforming growth factor beta 1 Homo sapiens
5 The lactate response on the EC network was diminished by TGF-beta1 neutralization, indicating a causal relationship between lactate and TGF-beta1 in the finely tuned processes of vessel formation and maturation which may also occur in vivo within tumor tissue. Lactic Acid transforming growth factor beta 1 Homo sapiens