Pub. Date : 2008 Mar
PMID : 17573783
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Endogenous morphine signaling via nitric oxide regulates the expression of CYP2D6 and COMT: autocrine/paracrine feedback inhibition. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 2 | Leukocyte exposure to morphine down-regulated catechol-O-methyl transferase (COMT) and CYP2D6 by approximately 50% compared with control values. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 3 | Leukocyte exposure to morphine down-regulated catechol-O-methyl transferase (COMT) and CYP2D6 by approximately 50% compared with control values. | Morphine | catechol-O-methyltransferase | Homo sapiens |
| 4 | The verification of the microarray data was accomplished via real-time Taqman reverse transcriptase polymerase chain reaction (RT-PCR) focused on CYP2D6 and COMT expression in different blood samples treated with morphine. | Morphine | catechol-O-methyltransferase | Homo sapiens |