Pub. Date : 2007 May
PMID : 17573710
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Benzo[a]pyrene-dependent activation of transcription factors NF-kappaB and AP-1 related to tumor promotion in hepatoma cell cultures. | Benzo(a)pyrene | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | The activation by the carcinogenic polycyclic aromatic hydrocarbon (PAH) benzo[a]pyrene (BP) of transcription factors NF-kappaB and AP-1 in hepatoma 27 and HepG2 cell cultures was studied. | Benzo(a)pyrene | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | The activation by the carcinogenic polycyclic aromatic hydrocarbon (PAH) benzo[a]pyrene (BP) of transcription factors NF-kappaB and AP-1 in hepatoma 27 and HepG2 cell cultures was studied. | Benzo(a)pyrene | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | The transcription factor NF-kappaB was activated only in the hepatoma 27 cells by BP treatment but not by its noncarcinogenic isomer benzo[e]pyrene (BeP). | Benzo(a)pyrene | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | It is concluded that the NF-kappaB activation is caused by nonmetabolized BP molecule and not related to activation of the Ah-receptor. | Benzo(a)pyrene | nuclear factor kappa B subunit 1 | Homo sapiens |