Title : Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

Pub. Date : 2007 Jul 13

PMID : 17569825






1 Functional Relationships(s)
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1 We identified the vitamin A metabolite retinoic acid as a key regulator of TGF-beta-dependent immune responses, capable of inhibiting the IL-6-driven induction of proinflammatory T(H)17 cells and promoting anti-inflammatory Treg cell differentiation. Tretinoin interleukin 6 Homo sapiens