Title : Role of p53 in antioxidant defense of HPV-positive cervical carcinoma cells following H2O2 exposure.

Pub. Date : 2007 Jul 1

PMID : 17567683






1 Functional Relationships(s)
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1 Inhibition of p53 resulted in excessive oxidation of DNA; control SiHa cells exhibited a more rapid removal of 8-oxo-7,8-dihydro-2"-deoxyguanosine from DNA compared with p53-deficient SiHa cells exposed to the same level of H2O2 challenge. 8-ohdg tumor protein p53 Homo sapiens