Pub. Date : 1991 Sep
PMID : 1756437
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of prostaglandin inhibition by indomethacin on plasma active and inactive renin concentration in men. | Indomethacin | renin | Homo sapiens |
| 2 | The effect of inhibition of prostaglandin synthesis by indomethacin on active renin and on acid-activable inactive renin was studied in nine healthy, sodium-replete men, both at rest and exercise. | Indomethacin | renin | Homo sapiens |
| 3 | Indomethacin induced a decrease in active (p = 0.004), total (p less than 0.001), and inactive (p = 0.02) renin at rest recumbent on average by 42, 19, and 8%, respectively, and at rest sitting on average by 45, 15, and 3%, respectively. | Indomethacin | renin | Homo sapiens |
| 4 | Inhibition of prostaglandins with indomethacin reduced (p less than 0.001) active and total renin at each level of work load but not (p = 0.32) inactive renin. | Indomethacin | renin | Homo sapiens |
| 5 | However, the exercise-induced stimulation (p less than 0.05) of active and total renin still occur during indomethacin. | Indomethacin | renin | Homo sapiens |