Pub. Date : 2007 Jul 1
PMID : 17561096
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 2 | The degradation of biogenic amines by monoamine oxidase A (MAO-A) generates reactive oxygen species (ROS) which participate in serotonin and tyramine signaling. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 3 | The degradation of biogenic amines by monoamine oxidase A (MAO-A) generates reactive oxygen species (ROS) which participate in serotonin and tyramine signaling. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 4 | The degradation of biogenic amines by monoamine oxidase A (MAO-A) generates reactive oxygen species (ROS) which participate in serotonin and tyramine signaling. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 5 | The degradation of biogenic amines by monoamine oxidase A (MAO-A) generates reactive oxygen species (ROS) which participate in serotonin and tyramine signaling. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 6 | This study aimed to investigate the role of ROS in the mitogenic signaling activated during tyramine and serotonin oxidation by MAO-A in smooth muscle cells (SMC). | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |
| 7 | Silencing MAO-A by siRNA, pharmacological MAO-A inhibitors (pargyline and Ro41-1049), and the antioxidant/ROS scavenger butylated hydroxytoluene (BHT) inhibited the signaling cascade, suggesting that ROS generated during tyramine oxidation by MAO-A are required. | Reactive Oxygen Species | monoamine oxidase A | Homo sapiens |