Pub. Date : 2008 Jan
PMID : 17560613
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Olmesartan blocks advanced glycation end products (AGEs)-induced angiogenesis in vitro by suppressing receptor for AGEs (RAGE) expression. | olmesartan | advanced glycosylation end-product specific receptor | Homo sapiens |
| 2 | Olmesartan significantly inhibited the AGEs-induced NF-kappaB promoter activity and RAGE gene expression in cultured microvascular endothelial cells (ECs). | olmesartan | advanced glycosylation end-product specific receptor | Homo sapiens |
| 3 | These results demonstrated for the first time that olmesartan inhibited the AGEs signaling to angiogenesis by suppressing RAGE expression in ECs. | olmesartan | advanced glycosylation end-product specific receptor | Homo sapiens |