Title : Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.

Pub. Date : 2007 Aug 15

PMID : 17555959






1 Functional Relationships(s)
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1 This paper describes the synthesis of orally available potent fXa inhibitors 2 and 3 by modification of the piperazine part of lead compound 1. Piperazine coagulation factor X Homo sapiens