Title : Point mutations involved in red cell stomatocytosis convert the electroneutral anion exchanger 1 to a nonselective cation conductance.

Pub. Date : 2007 Sep 15

PMID : 17554061






1 Functional Relationships(s)
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1 Our results show that the point mutations of hAE1 convert the electroneutral anion exchanger to a cation conductance: the exchangers are no longer able to exchange Cl(-) and HCO(3)(-), whereas they transport Na(+) and K(+) through a conductive mechanism. Bicarbonates solute carrier family 4 member 1 (Diego blood group) Homo sapiens