Title : Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.

Pub. Date : 2007 Sep

PMID : 17551504






1 Functional Relationships(s)
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1 By the transfection of constitutively active form of activin receptor-like kinase 6 (caALK6) and runt-related transcription factor 2 (Runx2), the osteogenic differentiation was induced on mouse calvarial cells to a greater extent than when poly(ethylenimine) (PEI) or FuGENE6 were used; this result was due to low cytotoxicity and a sustained gene expression profile. Polyethyleneimine bone morphogenetic protein receptor, type 1B Mus musculus