Title : Behavioral effects of dipropyltryptamine in rats: evidence for 5-HT1A and 5-HT2A agonist activity.

Pub. Date : 2007 Jul

PMID : 17551320






1 Functional Relationships(s)
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1 Pretreatment with DPT blocked 8-OH-DPAT-elicited lower-lip retraction, suggesting antagonist activity of DPT at 5-HT1A receptors; however, in the presence of MDL100907 DPT produced not only flat body posture but also lower-lip retraction, suggesting that agonist activity of DPT at 5-HT2A receptors masked agonist activity at 5-HT1A receptors. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Rattus norvegicus