Title : Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.

Pub. Date : 2007 Jun 12

PMID : 17535895






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS), resulting in decreased prenylation of small GTPases. Diphosphonates farnesyl diphosphate synthase Homo sapiens
2 Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS), resulting in decreased prenylation of small GTPases. Diphosphonates farnesyl diphosphate synthase Homo sapiens