Title : Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines.

Pub. Date : 2007 Nov

PMID : 17534580






1 Functional Relationships(s)
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1 Finally, a significant increase in caspase-3 activity and apoptosis was observed in the presence of both VPA and etoposide compared to either agent alone. Valproic Acid caspase 3 Homo sapiens