Title : The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain.

Pub. Date : 2007 Jun 1

PMID : 17534149






2 Functional Relationships(s)
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1 We and others have recently identified a novel modification on p53, acetylation of lysine 120 within the DNA binding domain. Lysine tumor protein p53 Homo sapiens
2 We demonstrate here that both the DNA damage response pathway and the p19ARF/oncogene stress pathway induce the acetylation of p53 at lysine 120. Lysine tumor protein p53 Homo sapiens