Title : Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix.

Pub. Date : 2007 Sep

PMID : 17532040






1 Functional Relationships(s)
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1 Cells within RGD-modified alginate microspheres were able to establish more interactions with the synthetic extracellular matrix as visualized by confocal laser scanning microscope and transmission electron microscopy imaging, and presented a much higher level of differentiation (more intense ALP and mineralization stainings and higher levels of osteocalcin secretion) when compared to cells immobilized within unmodified alginate microspheres. Alginates bone gamma-carboxyglutamate protein Homo sapiens