Title : Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts.

Pub. Date : 2007 Jun

PMID : 17530703






1 Functional Relationships(s)
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1 OBJECTIVE: Recently, Swedish members of the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) provided evidence that smoking may trigger RA-specific immune reactions to citrullinated protein in carriers of HLA-DR shared epitope alleles. Radium major histocompatibility complex, class II, DR beta 1 Homo sapiens