Title : Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats.

Pub. Date : 2007 May

PMID : 17523050






1 Functional Relationships(s)
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1 Testosterone 2alpha- and 16alpha-hydroxylation reactions were conducted primarily by CYP2C11, and midazolam 4-hydroxylation and triazolam 1"-hydroxylation were preferentially catalyzed by CYP3A1/2, but specificity was otherwise generally poor. Testosterone cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus