Title : Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2).

Pub. Date : 2007 Apr

PMID : 17520098






2 Functional Relationships(s)
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1 Furthermore, the results indicate that quercetin increased the content of Cdk inhibitor p21 protein, which was correlated with the elevation in p53 levels during 12 h of incubation. Quercetin tumor protein p53 Homo sapiens
2 From our results it can be concluded that quercetin blocks cell cycle progression at G(1) phase and exerts its growth-inhibitory effect through the increase of Cdk inhibitors p21 and p27 and tumor suppressor p53 in HepG2. Quercetin tumor protein p53 Homo sapiens