Title : Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.

Pub. Date : 2007 May 29

PMID : 17517611






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activation of the checkpoint kinase Rad53 is a critical response to DNA damage that results in stabilization of stalled replication forks, inhibition of late-origin initiation, up-regulation of dNTP levels, and delayed entry to mitosis. Parathion checkpoint kinase 2 Homo sapiens