Title : QSAR and mechanistic interpretation of estrogen receptor binding.

Pub. Date : 2007 May-Jun

PMID : 17514577






1 Functional Relationships(s)
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1 Analysis of reactivity patterns based on the distance between nucleophilic sites resulted in identification of distinct interaction types: a steroid-like A-B type described by frontier orbital energies and distance between nucleophilic sites with specific charge requirements; an A-C type where local hydrophobic effects are combined with electronic interactions to modulate binding; and mixed A-B-C (AD) type. Steroids ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens