Title : The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees?

Pub. Date : 2007 Aug

PMID : 17514356






1 Functional Relationships(s)
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1 These alterations may well be relevant to the therapeutic effects of valproate, and result from its enhancement of activator protein-1 DNA binding and direct inhibition of histone deacetylases, and possibly additional, yet unknown, mechanism(s). Valproic Acid JunD proto-oncogene, AP-1 transcription factor subunit Homo sapiens