Title : Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.

Pub. Date : 2007 Sep 1

PMID : 17510321






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 AZD6244 blocks constitutive and cytokine-stimulated ERK1/2 phosphorylation and inhibits proliferation and survival of human MM cell lines and patient MM cells, regardless of sensitivity to conventional chemotherapy. AZD 6244 mitogen-activated protein kinase 3 Homo sapiens