Title : Transient receptor potential vanilloid 1 activation induces inflammatory cytokine release in corneal epithelium through MAPK signaling.

Pub. Date : 2007 Dec

PMID : 17508360






1 Functional Relationships(s)
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1 Capsaicin (CAP) (1-10 microM) increased nonselective cation channel whole cell currents (2.5-fold +/- 0.5-fold between -60 and 130 mV), resulting in calcium transients that were fully blocked by the TRPV1 antagonists capsazepine (CPZ) and ruthenium red, or removal of extracellular calcium. Ruthenium Red transient receptor potential cation channel subfamily V member 1 Homo sapiens