Title : Molecular assessment of the potential for renal drug interactions between tenofovir and HIV protease inhibitors.

Pub. Date : 2007

PMID : 17503669






4 Functional Relationships(s)
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1 BACKGROUND: Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion transporters 1 and 3 (hOAT1 and hOAT3) coupled with efflux by multidrug resistance protein 4 (MRP4). Tenofovir solute carrier family 22 member 6 Homo sapiens
2 BACKGROUND: Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion transporters 1 and 3 (hOAT1 and hOAT3) coupled with efflux by multidrug resistance protein 4 (MRP4). Tenofovir solute carrier family 22 member 6 Homo sapiens
3 BACKGROUND: Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion transporters 1 and 3 (hOAT1 and hOAT3) coupled with efflux by multidrug resistance protein 4 (MRP4). Tenofovir solute carrier family 22 member 6 Homo sapiens
4 BACKGROUND: Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion transporters 1 and 3 (hOAT1 and hOAT3) coupled with efflux by multidrug resistance protein 4 (MRP4). Tenofovir solute carrier family 22 member 6 Homo sapiens