Pub. Date : 2007 Jun
PMID : 17502774
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased (R)-methadone plasma concentrations by quetiapine in cytochrome P450s and ABCB1 genotyped patients. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | The mean increases of (R)-methadone concentration-dose ratios were of 7%, 21%, and 30% in the CYP2D6 poor metabolizers, heterozygous EMs, and homozygous EMs, respectively, whereas they were of 3%, 23%, and 33% in the subjects with the ABCB1 3435 TT, CT, and CC genotypes, respectively. | Methadone | ATP binding cassette subfamily B member 1 | Homo sapiens |