Pub. Date : 2007 Jul 13
PMID : 17500071
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | sFRP-1 and Wnts are heparin-binding proteins, and their interaction can be stabilized by heparin in vitro. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 2 | Here we report that heparin can specifically enhance recombinant sFRP-1 accumulation in a cell type-specific manner. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 3 | Interestingly, further investigation uncovers that heparin can also affect the post-translational modification of sFRP-1. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 4 | We demonstrate that sFRP-1 is post-translationally modified by tyrosine sulfation at tyrosines 34 and 36, which is inhibited by the treatment of heparin. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 5 | The results suggest that accumulation of sFRP-1 induced by heparin is in part due to the relative stabilization of unsulfated sFRP-1 and the direct stabilization by heparin. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 6 | The results suggest that accumulation of sFRP-1 induced by heparin is in part due to the relative stabilization of unsulfated sFRP-1 and the direct stabilization by heparin. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 7 | The results suggest that accumulation of sFRP-1 induced by heparin is in part due to the relative stabilization of unsulfated sFRP-1 and the direct stabilization by heparin. | Heparin | secreted frizzled related protein 1 | Homo sapiens |
| 8 | The study has revealed a multifaceted regulation on sFRP-1 protein by heparin. | Heparin | secreted frizzled related protein 1 | Homo sapiens |