Title : UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway.

Pub. Date : 2007 Oct 18

PMID : 17496931






1 Functional Relationships(s)
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1 We demonstrate that in addition to topotecan (TPT), a known inhibitor of HIF-1alpha, UVC, but not other DNA damaging agents (cisplatin, ionizing radiation and doxorubicin), inhibited HIF-1alpha protein accumulation in a dose-dependent, p53-independent fashion. Topotecan tumor protein p53 Homo sapiens